Schizophrenia Mental and Behavioural Disorders Schizophrenia
Conditions
Interventions
Forty sedentary patients diagnosed with schizophrenia are allocated to a 1-year Guided Walking program (GW n=28), consisting of two walking sessions per week, or to a Cognitive Rehabilitation program
Sponsors
University of Ferrara
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with schizophrenia since at least 1 year 2. On antipsychotic medications with the same therapeutic regimen for at least 3 months before enrolment 3. Free of symptomatic peripheral arterial occlusive disease and cardiovascular, pulmonary, neurological, metabolic, and orthopaedic disorders that could interfere with the walking activity
Exclusion criteria
Exclusion criteria: 1. Recent modification of therapeutic regimen 2. Presence of symptomatic peripheral arterial occlusive disease and cardiovascular, pulmonary, neurological, metabolic, and orthopaedic disorders that could interfere with the walking activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Feasibility was evaluated through the number of dropouts between baseline the end of the study 2. Adherence was measured by the number of walking sessions attended by the participants during the one year program (using patient records) 2. Cognitive function assessed with the Screen for Cognitive Impairment in Psychiatry (SCIP) and the Frontal Assessment Battery (FAB) at baseline and after one year. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular risk factors were evaluated only in the subjects that followed the walking program (at baseline and after 1-year, at the end of the walking program): 1. Blood pressure (mmHg, sphygmomanometer) 2. Anthropometric variables - height (m), weight (kg), BMI (kg/m² and waist circumference (cm) 3. VO2peak was indirectly determined using the 1-kilometer walking test (1k-WT). Five minutes of slow walking preceded the test. Subjects were instructed to select a pace that they could maintain for 10 to 20 min at a moderate perceived exercise intensity, (11–13 on the 6–20 Borg scale). Heart rate was monitored continuously using a Polar Accurex Plus heart rate monitor (Polar Electro, Kempele, Finland). The equation for VO2 peak determination considering age, BMI, HR and time to complete the 1 k-TWT was then applied | — |
Countries
Italy
Outcome results
None listed