Denture stomatitis caused by Candida albicans Oral Health Other forms of stomatitis
Conditions
Interventions
Fifty adult denture wearers affected by denture stomatitis were enrolled and randomly divided into two groups: the experimental group was instructed to perform careful oral and denture hygiene and to
the control group received only conventional hygiene instructions to clean dentures. Patients were evaluated for signs of DS at the beginning, the end and 30 days after the treatment. Microbiological
Sponsors
Pharmextracta SpA
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. At least one totally edentulous dental arch 2. A full arch well-fitting removable acrylic denture 3. Subjective discomfort/pain in relation to denture 4. Clinical signs of denture stomatitis
Exclusion criteria
Exclusion criteria: 1. Use of adhesives for denture stabilization 2. Assumption of antibiotics in the last 30 days 3. Systemic diseases influencing homeostasis of the oral mucosae
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Presence/absence of subjective pain in the oral mucosae assessed by asking patients at 30 and 60 days 2. Presence/absence of sensation of dryness of the mouth assessed by asking patients at 30 and 60 days 3. Visual signs of denture stomatitis assessed by clinical observation made by clinician using Newton's classification at 30 and 60 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number of Candida albicans (cfu/ml) measured from a specimen obtained by streaking a cotton swab along the gingiva, at 0 and 30 days 2. Number of Candida albicans (cfu/ml) measured from a specimen of saliva at 0 and 30 days | — |
Countries
Italy
Outcome results
None listed