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WELCOME: improving WEight controL and CO-Morbidities in children with obesity via Executive function training

Improving weight control and co-morbidities in children with obesity via executive function training: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN14722584
Enrollment
200
Registered
2017-06-16
Start date
2017-04-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childhood obesity Nutritional, Metabolic, Endocrine Obesity

Interventions

Participants are randomized to either an experimental group or an active control group (50/50, 30/10 in pilot) via the OPEN CLINICA computer program. The executive function training consists of two ta

Sponsors

Ghent University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Obese youngsters ((a)BMI > 120) 2. Age 8 - 18 3. Both male and female 4. Following treatment (outpatient or inpatient)

Exclusion criteria

Exclusion criteria: Comorbid medical disorders that cause (a part of) the weight gain (i.e. serious thyroid problems)

Design outcomes

Primary

MeasureTime frame
Weight index (BMI, adjusted, calibrated) measured at T0-T4 Timepoints: T0 = baseline (at the intake in the treatment centre) T1 = start training (in between there is approximately 4-6 months, depending on the treatment centre) T2 = end of the intensive training (after 6 weeks intensive training and when the follow-up and booster starts) T3 = after 2 months/8 weeks follow up and performing the tasks once a week in booster sessions T4 = after 6 months follow up

Secondary

MeasureTime frame
1. IQ, measured using Raven Progressive Matrices (task for the participant) at T0-T4, except for the outpatient centers that don’t measure them at T1 2. Depression and anxiety, measured using ASEBA questionnaires: Youth Self Report (YSR) and Child Behavior Checklist (CBCL) and the Children Depression Inventory (CDI) self-report at T0-T4, except for the outpatient centers that don’t measure them at T1 3. Self-worth, measured using CBSA and CBSK, translated version of Self-Perception Profile at T0-T4, except for the outpatient centers that don’t measure them at T1 4. Executive functioning, measured using: 4.1. A questionnaire (Effortful Control Scale (ECS) self-report, BRIEF (Behavior Rating Inventory of Executive Function) = BRIEF-Parent version and BRIEF-teacher version [for the educators at the Zeepreventorium]) at all timepoints, with exclusion of the T1 measurements for the outpatient settings 4.2. Inhibition and attention measurements from the EF tasks (Go-No-Go and Dot Probe Task), errors and reaction times at T0, T1, T2, T3 and T4 5. Eating behaviors, measured using Ch-EDE-Q self-report and Dutch Eating Behavior Questionnaire (“NVE” in Dutch) at T0-T4, except for the outpatient centers that don’t measure them at T1 Added 21/06/2017: Medical variables: 1. Waist and hip measurements at T1 + T3 2. Blood and pulse pressure, measured with automatic meters 3. Puberty status: clinical stages (Tanner) 4. Tonsillar hypertrophy: clinical stages (Brodsky) 5. Blood measurements (venipuncture) 6. Urine (urine sample) 7. Lung function, measured with spirometry and full body plethysmography 8. Vascular function, measured with ENDO-Pat 9. Sleep pattern, measured with ApneaLink and questionnaire 10. Body composition, measured with a Body Composition Monitor (BCM) Timepoints: T0 = baseline (at the intake in the treatment centre) T1 = start training (in between there is approximately 4-6 months, depending on the treatment centre) T2 = end of the intensive training (after 6 w

Countries

Belgium

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 23, 2026