A study to test a new way of more accurately measuring kidney function using fingerprick blood samples

Improving the accuracy of chronic kidney disease monitoring using postal finger prick iohexol measured glomerular filtration rate

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN14717076

Enrollment

Registered

2022-07-28

Start date

2022-08-02

Completion date

Unknown

Last updated

2022-08-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with chronic kidney disease (CKD) where creatinine-based eGFR calculation may give spurious results Urological and Genital Diseases

Interventions

Patients will be recruited from the renal outpatient department. Patients will receive a 5 ml bolus of Omnipaque followed by paired venous and fingerprick bloods 5 minutes post injection (time zero).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients with CKD

Exclusion criteria

Exclusion criteria: 1. Iodine intolerance 2. Unable to provide consent 3. Unable to perform fingerprick blood testing

Design outcomes

Primary

Measure	Time frame
Bland Altman comparison of fingerprick versus “gold standard” venous iohexol levels at time 0 using bias and P30 measurements	—

Secondary

Measure	Time frame
Percentage of participants in whom mGFR results differ from clinically used eGFR results to the extent that treatment is likely to have differed (e.g. drug dosing) had mGFR been used for clinical decision making at the time of study visit	—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026