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Fruit juice, fruit, and cardiovascular diseases

Pure fruit juice and fruit consumption and the risk of cardiovascular diseases: the EPIC-NL study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN14659829
Enrollment
40000
Registered
2018-01-29
Start date
1993-01-11
Completion date
Unknown
Last updated
2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular diseases, coronary heart diseases and stroke Circulatory System

Interventions

A validated FFQ was used to estimate the dietary intake of 35,620 Dutch men and women from the EPIC-NL study. CVD, CHD and stroke morbidity and mortality data were obtained through linkage with nation

Sponsors

Netherlands Organisation for Scientific Research (NWO)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The EPIC-NL study consists of two cohorts: 1. The MORGEN cohort consists of men and women aged 20 – 65 years selected from random samples of the Dutch population in three towns in the Netherlands (Amsterdam, Doetinchem, Maastricht) 2. The Prospect cohort consists of women from the Dutch town Utrecht or its vicinity, who participated in a breast cancer screening program

Exclusion criteria

Exclusion criteria: 1. Missing food-frequency questionnaire (FFQ) 2. Extremely low or high reported energy intake (i.e. those in the lowest or highest 0.5% of the ratio of energy intake over basal metabolic rate) 3. No permission to link with the Dutch Hospital Discharge Diagnosis Database 4. Missing vital status 5. Missing cause of death 6. Prevalent CVD at baseline based on self-report or identified through linkage with the Dutch Hospital Discharge Diagnosis Database 7. Prevalent Diabetes Mellitus at baseline based on self-report, or missing data on confounders

Design outcomes

Primary

MeasureTime frame
CVD morbidity and mortality data obtained through linkage with national registries from baseline (1993 – 1993) to 2010

Secondary

MeasureTime frame
CHD and stroke morbidity and mortality data obtained through linkage with national registries from baseline (1993 – 1993) to 2010

Countries

Netherlands

Contacts

Public ContactFloor Scheffers

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026