Effect of hyaluronic acid on the oral mucosa healing after diode laser biopsies

Studying the effect of hyaluronic acid on mucosal healing after excisional oral biopsies with 810 nm diode laser

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14643405

Enrollment

Registered

2024-09-06

Start date

2023-07-01

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mucosal healing after oral excisional biopsies Oral Health

Interventions

This study is designed to evaluate the effect of hyaluronic acid (HA

Mouthwash - Gel) on mucosal healing after oral excisional biopsies with an 810 nm diode laser. A simple method of randomisation is used that involves writing the group name (A, B, C) on a piece of pa

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients that have oral fibromas on the non-keratinized oral mucosa 2. Excisional biopsy wounds with a diameter of less than 10mm

Exclusion criteria

Exclusion criteria: 1. People who have systemic diseases 2. Smokers 3. Alcoholics

Design outcomes

Primary

Measure	Time frame
Excision wound area measured using the Percentage Healing Index (PHI) after the excision immediately (T0), at day 4 (T1), week 1 (T2), week 2 (T3), and 1 month (T4)	—

Secondary

Measure	Time frame
Pain is measured using a Visual Analogue Scale ( VAS) at day 4, week 1, week 2, and 1 month	—

Countries

Syria

Contacts

Public ContactAmr Alyafi

amr.alyafi97@damascusuniversity.edu.sy+963947880112

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026