Prediction of non-invasive failure in pneumonia patients with acute lung injury Respiratory Influenza and pneumonia
Conditions
Interventions
All patients admitted to the ICU for NIV due to pneumonia with hypoxemic respiratory failure and mild to moderate ARDS i.e. P/F ratio 92%. At the beginning of treatment, continuous use of NIV is enco
Sponsors
Cairo University Hospitals
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. All patients admitted to the ICU for NIV due to pneumonia with hypoxemic respiratory failure and mild to moderate ARDS i.e. P/F ratio <300 2. Diagnosis of pneumonia established upon clinical findings and radiologic findings, compatible with pneumonia diagnosis
Exclusion criteria
Exclusion criteria: 1. Presence of do-not-intubate orders 2. Presence of chronic obstructive pulmonary disease 3. Requirement for emergency intubation 4. Severe ARDS i.e. P/F ratio < 150 5. NIV intolerance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIV failure, defined as the transition of the patient to invasive ventilation due to worsening clinical condition (drop in blood pressure or drop in conscious level), worse blood gases (increase in carbon dioxide or drop in oxygen), or patient refusal to continue on non-invasive ventilation. Timepoints: within the first 48 hours of non-invasive intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Prediction of non-invasive failure using the HACOR score calculated at 0, 1, 12, 24 hours | — |
Countries
Egypt
Outcome results
None listed