Myalgic encephalomyelitis Nervous System Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The International Consensus Criteria (ICC) will be used for people with ME. People with different severities of ME will be recruited ranging from mild to severe ME. 20 people without ME will be matched to the ME participants based on age and gender. They will be recruited from the University of Liverpool student and staff population and family members and friends of the ME participants. Additional inclusion criteria: 1. No history of medical conditions 2. Able to give informed consent
Exclusion criteria
Exclusion criteria: 1. People with very severe ME 2. Unable to take self-measurements with the portable lactic acid monitor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lactate measured using a Lactate Pro-2 monitor over 3 days, day 1, day 2 and day 3 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Fatigue and ME symptoms measured with the Depaul Symptom Questionnaire - short form - once on assessment 2. Physical function measured with the PROMIS Short form - fatigue - once on assessment 3. Fatigue measured with the PROMIS Short form - physical function - once on assessment | — |
Countries
England, United Kingdom, Wales