Testing a novel home-based approach for strengthening motor pathways

Strengthening residual motor pathways in individuals with spinal cord injury

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14598016

Enrollment

Registered

2026-04-16

Start date

2026-05-04

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Individuals who have had a cervical spinal cord injury which resulted in hand weakness Nervous System Diseases

Interventions

This study uses a randomised crossover design. Participants are allocated to one of two groups via randomisation (computer randomisation). Both groups receive the same intervention but in different or

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. >1 year post injury 2. Have a cervical spinal cord injury (C2-C7) resulting in hand weakness 3. Able to make a well-timed hand movement

Exclusion criteria

Exclusion criteria: 1. Uncontrolled medical problems including pulmonary, cardiovascular or orthopaedic disease 2. Psychosis or altered cognitive status which would affect consent 3. History of head injury or stroke 4. Fitted with cardiac pacemaker (a contraindication for TMS) 5. Metal plate in skull (a contraindication for TMS) 6. History of seizures (a contraindication for TMS) 7. Pregnant females 8. Ongoing cord compression or a syrinx in the spinal cord or spinal cord disease such as spinal stenosis, spina bifida or herniated cervical disk 9. An aversion to loud sounds

Countries

England, United Kingdom

Contacts

Public ContactLillian Clements

lillian.clements@newcastle.ac.uk+44 7951202024

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: May 1, 2026