NEUROlogic rehabilitation with GAIT training using body weight support and music-based feedback

NEUROGAIT Study – the effect of body weight supported treadmill training combined with neurologic music therapy on gait parameters and locomotor symmetry in neurological patients: a prospective randomized controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14585687

Enrollment

Registered

2026-02-03

Start date

2025-07-01

Completion date

Unknown

Last updated

2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effectiveness of a therapeutic intervention consisting of body weight–supported treadmill training combined with neurologic music therapy in neurological patients (post-stroke, spinal cord injury, multiple sclerosis) undergoing inpatient rehabilitation. Nutritional, Metabolic, Endocrine

Interventions

The study is designed as a prospective, randomized controlled trial with assessments at baseline (T0), after completion of therapy (T1), and with an optional follow-up assessment (T2) at 4 weeks. Rec

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18–80 years 2. Sex/Gender: Women and men; no sex-based recruitment preferences 3. Neurological diagnosis (e.g., ischemic or hemorrhagic stroke, spinal cord injury, multiple sclerosis) 4. Time since neurological event: =3 weeks; up to several years (stable subacute or chronic phase) 5. Mobility status: Able to ambulate with an orthopedic aid and/or therapist assistance 6. Medical fitness: Clinical status permitting participation in gait training (as assessed by the attending physician and physiotherapist) 7. Cognitive capacity: Sufficient to understand instructions and provide written informed consent

Exclusion criteria

Exclusion criteria: 1. Unstable cardiac or pulmonary disease 2. Severe cognitive impairment (MMSE 3) 4. History of orthopedic surgery, preventing gait training 5. Hypersensitivity or significant discomfort related to sounds or music6

Design outcomes

Primary

Measure	Time frame
1. Change in spatiotemporal gait parameters (step length, gait speed, gait cycle) measured using the Biodex Gait Trainer 3 from baseline (T0) to post-intervention (T1) 2. Change in gait symmetry, assessed by stance time and step length (right vs. left limb) and coefficient of variation within the gait cycle, measured with the Biodex Gait Trainer 3 from T0 to T1 3. Comparison of locomotor outcomes between groups (treadmill training with vs. without neurologic music therapy), including patients using orthopedic aids (cane, crutch, walker), measured with Biodex Gait Trainer 3 from baseline (T0) to post-intervention (T1)	—

Measure

Time frame

1. Change in spatiotemporal gait parameters (step length, gait speed, gait cycle) measured using the Biodex Gait Trainer 3 from baseline (T0) to post-intervention (T1) 2. Change in gait symmetry, assessed by stance time and step length (right vs. left limb) and coefficient of variation within the gait cycle, measured with the Biodex Gait Trainer 3 from T0 to T1 3. Comparison of locomotor outcomes between groups (treadmill training with vs. without neurologic music therapy), including patients using orthopedic aids (cane, crutch, walker), measured with Biodex Gait Trainer 3 from baseline (T0) to post-intervention (T1)

—

Secondary

Measure	Time frame
The following functional independence and mobility secondary outcomes will be assessed from T0 to T1 (and T2, optional) using: 1. Barthel Index 2. Timed Up and Go (TUG) 3. 10-Meter Walk Test (10MWT) 4. Rivermead Motor Assessment – Gross Function 5. Patient Locomotion Ability Form (classification of mobility with/without aids) 6. Modified Ashworth Scale (muscle tone) 7. Medical Research Council (MRC) Scale (muscle strength) 8. ICF Short Assessment 9. Change in the use of orthopedic aids (walker, cane, crutches), documented at T0, T1, and T2 10. Health-related quality of life using the WHOQOL-BREF (or EQ-5D, depending on availability), from T0 to T1 (and T2)	—

Measure

Time frame

The following functional independence and mobility secondary outcomes will be assessed from T0 to T1 (and T2, optional) using: 1. Barthel Index 2. Timed Up and Go (TUG) 3. 10-Meter Walk Test (10MWT) 4. Rivermead Motor Assessment – Gross Function 5. Patient Locomotion Ability Form (classification of mobility with/without aids) 6. Modified Ashworth Scale (muscle tone) 7. Medical Research Council (MRC) Scale (muscle strength) 8. ICF Short Assessment 9. Change in the use of orthopedic aids (walker, cane, crutches), documented at T0, T1, and T2 10. Health-related quality of life using the WHOQOL-BREF (or EQ-5D, depending on availability), from T0 to T1 (and T2)

—

Countries

Poland

Contacts

Public ContactWojciech T. Laber

wojciech.t.laber@umw.edu.pl+4871/784 28 15

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026