The effect of retrograde autologous priming of cardiopulmonary bypass circuit on jugular bulb venous oxygen saturation compared with conventional priming: a prospective randomised comparative study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14583192

Enrollment

Registered

2003-09-12

Start date

2002-08-31

Completion date

Unknown

Last updated

2020-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery bypass grafting (CABG) Surgery

Interventions

Randomised controlled trial. Random allocation to: 1. Conventional priming of cardiopulmonary bypass circuit 2. Retrograde autologous priming of bypass circuit

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 20 Patients scheduled to undergo first time coronary artery bypass grafting will be recruited. They will be American Society of Anaesthesiologist grade III or less.

Exclusion criteria

Exclusion criteria: 1. History of cerebrovascular disease 2. Diabetes mellitus 3. Body weight less than 60 kg 4. Haemoglobin level of less than 11g/dl 5. Refusal to receive blood products

Design outcomes

Primary

Measure	Time frame
To compare SjvO2 values immediately after establishing full cardiopulmonary bypass pump flow.	—

Secondary

Measure	Time frame
Further SjvO2 values and Lactate - Oxygen Indices.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026