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Modification of chronic oral nonsteroidal anti-inflammatory drug (NSAID) requirement; feasibility, patient benefit and cost-effectiveness.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN14558398
Enrollment
260
Registered
2004-01-23
Start date
1995-10-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Patients will be randomised, stratified according to joint or non-joint disorder, to receive either: 1. General advice on NSAIDs (group 1) 2. Reduced NSAIDs plus advice on alternative treatments for t

Sponsors

NHS R&D Regional Programme Register - Department of Health (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Two general practices with computer generated register data will be invited to participate. Up to 260 patients receiving regular prescriptions for NSAIDs for regional locomotor pain will be identified according to the following criteria. 1. Adult (18 years or older, no upper age limit) 2. Oral NSAID prescriptions to cover at least 6 of the previous 12 months 3. Last prescription within 6 weeks of induction into study 4. Osteoarthritis or regional locomotor pain (e.g. shoulder lesion, neck pain, back pain) as the reason for prescription

Exclusion criteria

Exclusion criteria: Defined inflammatory arthritis (e.g. rheumatoid arthritis, ankylosin spondylitis, gout), bone malignancy or non-locomotor pain as reason for prescription (obtained from GP records)

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026