Induction of true remission in early poor prognosis (erosive) rheumatoid arthritis (RA) - a randomised study of methotrexate and intra-articular corticosteroids or placebo

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14554919

Enrollment

Registered

2002-07-15

Start date

1995-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early rheumatoid arthritis Musculoskeletal Diseases Rheumatoid arthritis

Interventions

1. Receive combination therapy (n = 40) 2. Receive sulfasalazine (SSZ) alone (n = 42)

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients to meet the American College of Rheumatology criteria for RA 2. Poor prognosis disease according to criteria based on the presence of factors known to be predictive of poor long-term outcome 3. Adequate contraception a prerequisite

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Not provided at time of registration	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026