A radiostereometry assessment of bone graft in hip revision surgery

A radiostereometry assessment of bone graft processed with novel sterilisation techniques (a study of patients undergoing acetabular impaction grafting hip revision surgery).

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14542389

Enrollment

Registered

2016-05-24

Start date

2014-09-20

Completion date

Unknown

Last updated

2017-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Revision Hip replacement surgery Musculoskeletal Diseases

Interventions

A prospective study is being carried out on 50 patients undergoing impaction revision of the acetabulum for aseptic loosening of primary total hip replacement for osteoarthritis. Patients are randomis

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age 50-80 2. First revision of cemented THR 3. Acetabular defects suitable for Impaction grafting

Exclusion criteria

Exclusion criteria: 1. Previous surgery for inflammatory arthritis of the hip 2. Renal transplant or significant renal impairment 3. Immunosuppressive condition or recent high dose steroids 4. Known or suspected ipsilateral hip infection 5. Neurological disease limiting rehabilitation e.g. Parkinson?s 6. Psychosocial disorders likely to limit rehabilitation 7. Geographical factors making follow up impractical 8. Other condition severely limiting life expectancy 9. Dementia or other condition affecting ability to give consent 10. Revision for periprosthetic fracture or dislocation 11. Facility for intraoperative exclusion (e.g. periprosthetic fracture, uncontained defect, suspected sepsis

Design outcomes

Primary

Measure	Time frame
Migration and inducible movement of cemented acetabular components impacted. Each patient will be evaluated using standard weight bearing and non-weight bearing RSA radiographs at time of discharge, at six weeks, three months, six months, one year and two years after surgery. In addition, each patient will receive one repeat examination for clinical precision estimate in accordance with RSA guidelines.	—

Measure

Time frame

Migration and inducible movement of cemented acetabular components impacted. Each patient will be evaluated using standard weight bearing and non-weight bearing RSA radiographs at time of discharge, at six weeks, three months, six months, one year and two years after surgery. In addition, each patient will receive one repeat examination for clinical precision estimate in accordance with RSA guidelines.

—

Secondary

Measure	Time frame
1. Joint function, assessed using the Oxford Hip Score before surgery and again 12 months after surgery 2. General health,assessed using the Euroquol 5D score before surgery, 12 months after surgery and 24 months after surgery 3. Assessment of a hip arthroplasty via plain x-ray - radiolucency before surgery, just after surgery, then again at 12 months and 24 months	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026