Alcohol dependence Mental and Behavioural Disorders Alcohol dependence
Conditions
Interventions
Individuals who visit the clinics undergo customary diagnostic procedures, and are thereafter asked for participation in the study. Individuals who indicate a positive response are then informed about
Sponsors
Karolinska Institutet
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Fulfils criteria for alcohol use disorder according to DSM5 2. Aged 18-70 years 3. Has an explicit goal of reducing current alcohol consumption 4. Alcohol consumption during at least 30 of the last 90 days before inclusion 5. Stable housing in the Stockholm region 6. Willingness to give informed consent.
Exclusion criteria
Exclusion criteria: 1. Has complete abstinence as target for treatment 2. Severe somatic or psychiatric problems 3. Pregnant 4. Current drug use (during the past 3 months) 5. Harmful use of or dependence on substance other than alcohol (except nicotine)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current primary outcome measure as of 04/10/2022: Mean weekly alcohol consumption during the time period 90 days before inclusion compared with 6 months post inclusion Previous primary outcome measure: Percentage of days with binge drinking (men: >60 g alcohol per occasion; women: >48 g alcohol per occasion) during the time period 90 days before inclusion compared with at 6, 12, and 24 months post inclusion. | — |
Secondary
| Measure | Time frame |
|---|---|
| Current secondary outcome measures as of 04/10/2022: 1. Percentage of days with binge drinking (men: >60 g alcohol per occasion; women: >48 g alcohol per occasion) compared with 6, 12, and 24 months post inclusion 2. Percentage of weeks with harmful use (men: >168 g/week; women: >108 g/week) during the time 90 days before inclusion compared with 6, 12, and 24 months post inclusion 3. Percentage of weeks with consumption according to individual goal from the time of inclusion until 6, 12 and 24 months post inclusion 4. Degree of dependence at inclusion compared at 12 and 24 months post inclusion 5. Biological markers of alcohol consumption at inclusion, compared with 6, 12, and 24 months post inclusion 6. Alcohol-related medical, psychological and social consequences of alcohol consumption at inclusion compared with 6, 12 and 24 months post inclusion 7. Self-reported alcohol craving at inclusion compared with 6, 12, and 24 months post inclusion 8. Degree of loss of control of consumption at inclusion compared with 6, 12, and 24 months post inclusion Previous secondary outcome measures: 1. Percentage of days with drinking during the time 90 days before inclusion compared with 6, 12, and 24 months post inclusion 2. Percentage of weeks with harmful use (men: >168 g/week; women: >108 g/week) during the time 90 days before inclusion compared with 6, 12, and 24 months post inclusion 3. Percentage of weeks with consumption according to individual goal from the time of inclusion until 6, 12 and 24 months post inclusion 4. Degree of dependence at inclusion compared at 12 and 24 months post inclusion 5. Biological markers of alcohol consumption at inclusion, compared with 6, 12, and 24 months post inclusion 6. Alcohol-related medical, psychological and social consequences of alcohol consumption at inclusion compared with 6, 12 and 24 months post inclusion 7. Self-reported alcohol craving at inclusion compared with 6, 12, and 24 months post inclusion 8. Degree of loss of cont | — |
Countries
Sweden
Outcome results
None listed