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Is early colonoscopy in patients with acute rectal blood loss better than standard colonoscopy?

Early versus standard colonoscopy: A randomised controlled trial in patients with acute lower gastro-intestinal bleeding

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN14530195
Enrollment
132
Registered
2017-07-26
Start date
2013-05-08
Completion date
Unknown
Last updated
2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroenterology Digestive System Gastroenterology

Interventions

Patients presenting at the emergency department with acute hematochezia are consecutively included in the trial when they had an indication for clinical colonoscopy, according to the Dutch Guideline ‘

Sponsors

Research Fund of the Haaglanden Medical Centre
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18 years or over 2. Last bloody bowel movement within 24 hours of presentation 3. Ability to provide informed consent 4. No suspicion of or exclusion of an upper gastrointestinal bleeding source

Exclusion criteria

Exclusion criteria: 1. Known or suspected acute ischemic bowel, perforation or peritonitis 2. Hemodynamic instability refractory to resuscitation 3. Coagulopathy refractory to correction 4. Documented pregnancy 5. Serious comorbidities that would preclude the use of colonoscopy in standard clinical practice (i.e. severe COPD, severe cardiovascular comorbidity) 6. Decreased level of consciousness.

Design outcomes

Primary

MeasureTime frame
Hospital length of stay (in days) is measured calculated using the date and time of admission to hospital and the date and time of hospital discharge.

Secondary

MeasureTime frame
1. The yield of colonoscopy, defined as diagnosing either a confirmed or presumptive source of bleeding and treatment if feasible is obtained from electronic patient charts (colonoscopy reports) 2. The number of packed red blood cells is obtained from the electronic patient charts 3. Information on readmissions and the reason for readmission (rectal blood loss) is obtained from the electronic patient chart 4. Information on complications are obtained from the electronic patient chart 5. 30 day mortality is obtained from the electronic patient chart

Countries

Netherlands

Contacts

Public ContactInge van Rongen

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026