Determination of capillary blood concentrations of the oral antidiabetics metformin and/or sitagliptin in dried blood spots

Cross-sectional study to determine real-life concentrations of metformin and/or sitagliptin in patients with type 2 diabetes in dried blood spots

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN14518136

Enrollment

250

Registered

2016-07-28

Start date

2016-08-01

Completion date

Unknown

Last updated

2019-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus Nutritional, Metabolic, Endocrine Type 2 diabetes mellitus

Interventions

Capillary blood of type 2 diabetic patients will be collected in participating community pharmacies. The blood will be spotted on a filter paper, dried and sent for analysis of metformin, sitagliptin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with type 2 diabetes mellitus under therapy with metformin and/or sitagliptin 2. Patients older than 18 years

Exclusion criteria

Exclusion criteria: Patients with an infective disease

Design outcomes

Primary

Measure	Time frame
Metformin and/or sitagliptin concentrations in capillary blood samples using the dried blood-spot technique	—

Secondary

Measure	Time frame
Potential co-variates which might influence the concentrations such as estimated kidney function or co-medication	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026