Pain after knee joint replacement surgery Signs and Symptoms Pain after knee joint replacement surgery
Conditions
Interventions
Participants are randomly allocated to one of two groups.
Group 1: Participants will receive a standard general anaesthetic with standard monitoring. In addition, the joint will be infiltrated with t
Sponsors
Abertawe Bro Morgannwg University Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Primary knee replacement 2. Aged between 18 to 80 years 3. Able to give valid consent 4. No history of chronic pain unrelated to knee pain 5. No history of extensive trauma to the joint
Exclusion criteria
Exclusion criteria: 1. Lack of capacity for consent 2. Neuropathic pain / sensory disorders in leg to be operated on 3. Diabetes Mellitus 4. Previous major bone surgery in the knee to be operated on 5. Intolerance to study drugs 6. Local infection at site of operation 7. Significant GORD 8. BMI greater than 30 9. ASA 4/5 10. Long term opioid usage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain will be measured using the Numerical Rating Score of pain over a 48 hour period after surgery collected at 8am, 12pm, 5pm and 10pm on each day. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Opioid use over the first 48 hours after surgery is recorded by blind assessors throughout each patient's hospital stay 2. Time to mobilisation after surgery will be determined by recording walking distance, ability to complete leg lifts and range of motion during physiotherapy 4 hours post-surgery, 1 and 2 days post-surgery | — |
Countries
United Kingdom
Outcome results
None listed