Enamel White Spot Lesions [WSL] Oral Health
Conditions
Interventions
Participants will be randomly assigned, using computer generated numbers, blindly to intervention care (Bio-Min toothpaste) or standardised care (Conventional toothpaste), and assessed for the level o
Sponsors
Queen Mary University of London
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Age 12-18 years 2. Undergone a minimum of 12-months of fixed appliance treatment in both arches 3. Clinically identifiable WSL present on at least 1 of the maxillary and/or mandibular anterior teeth [first premolar to first premolar] at the time of removal of fixed orthodontic appliances
Exclusion criteria
Exclusion criteria: 1. Undergone previous course of fixed appliance treatment 2. Pre-existing clinical evidence of either enamel structural defects, demineralised lesions or fluorosis prior to commencement of treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Remineralisation of WSL measured using the method described by Willmot et al., [2000] as % change from baseline at 1, 3, 6 and 9 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Time interval for remineralisation measured using the method described by Willmot et al., [2000] at 1, 3, 6 and 9 months | — |
Countries
England, United Kingdom
Outcome results
None listed