Patients who need to perform an oral biopsy due to different oral conditions. Oral Health Patients who need to perform an oral biopsy due to different oral conditions.
Conditions
Interventions
After participants undergo the standard care for histological determination of oral lesions (oral biopsy), they are then randomly allocated to one of three groups. Allocation to the groups is performe
Sponsors
University of Turin
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Consecutive caucasian patients, attending the Oral Medicine Section of the Department of Surgical Sciences, Turin Hospital 2. Patients are those normally referred for histological determination of oral lesions 3. Adults aged 18 and older
Exclusion criteria
Exclusion criteria: 1. Clinically significant medical history (e.g. systemic infective disease, heart and vascular disease, liver disease, haematological disease, deficiency of the coagulation, diabetes and neoplastic disease) 2. Immunosuppressed or immunocompromised or those who received radiotherapy to the head and neck area 3. Already under antibiotic treatment for any other reasons or treated or under treatment with intravenous amino-bisphosphonates 4. Pregnant or lactating females; patients with incapacity to understand verbal and written instructions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Quality of life is detailed by the patients using the Italian version of the oral health related quality of life questionnaire measured by the Oral Health Impact Profile-14 (OHIP-14) at day six 2. Post-operative pain is detailed by the patients using a Visual Analogue Scale (VAS) at baseline, day one, three, and six | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Early post-operative complications are detailed during the clinical evaluation at day seven 2. Healing of biopsy site is measured during the clinical evaluation at day seven | — |
Countries
Italy
Outcome results
None listed