Dementia prevention for older people suffering from mild cognitive impairment using computerised cognitive training tools

Individualised computerised cognitive training for community-dwelling people with mild cognitive impairment

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14437015

Enrollment

100

Registered

2020-02-27

Start date

2020-06-09

Completion date

Unknown

Last updated

2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment (MCI) Mental and Behavioural Disorders Mild cognitive impairment

Interventions

Current interventions as of 23/06/2020: The goal is to develop a specialized digital cognitive training for persons with MCI that can be used from home with a computer, laptop or tablet. Study partic

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Current inclusion criteria as of 23/06/2020: 1. Mild cognitive impairment 1.1. Montreal Cognitive Assessment score 55 4. Informed consent given

Exclusion criteria

Exclusion criteria: 1. Completely blind or deaf 2. No personal computer, laptop or tablet 3. Normal cognition, Montreal Cognitive Assessment score =24 4. Dementia, Mini Mental Status Examination score <24 5. Depression, Patient Health Questionnaire 9 score =12 6. Apparent neurological diseases and/or other severe psychiatric diseases

Design outcomes

Primary

Measure	Time frame
Current primary outcome measure as of 14/12/2020: Cognition measured by the Montreal Cognitive Assessment (MoCA) at baseline and after 6 months _____ Previous primary outcome measure as of 23/06/2020: Cognition measured by the Montreal Cognitive Assessment (MoCA) at baseline and after 6 and 12 months _____ Previous primary outcome measure: Cognition measured by the Montreal Cognitive Assessment (MoCA) and Syndrom-Kurz-Test (SKT) at baseline and after 6 months	—

Measure

Time frame

Current primary outcome measure as of 14/12/2020: Cognition measured by the Montreal Cognitive Assessment (MoCA) at baseline and after 6 months _____ Previous primary outcome measure as of 23/06/2020: Cognition measured by the Montreal Cognitive Assessment (MoCA) at baseline and after 6 and 12 months _____ Previous primary outcome measure: Cognition measured by the Montreal Cognitive Assessment (MoCA) and Syndrom-Kurz-Test (SKT) at baseline and after 6 months

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Secondary

Measure	Time frame
Current secondary outcome measures as of 14/12/2020: 1. Cognition measured by reaction time and logical thinking assessments delivered and collected by the digital software at baseline and after 1, 2, 3, 4, 5 and 6 months and by the Mini-Mental Status Examination (MMSE) at baseline and after 6 months Exploratory outcome measures: Long-term cognitive status assessed using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental Status Examination (MMSE), yearly in the open phase _____ Previous secondary outcome measures as of 23/06/2020: 1. Cognition measured by reaction time and logical thinking assessments delivered and collected by the digital software at baseline and after 1, 2, 3, 4, 5 and 6 months, Mini-Mental Status Examination (MMSE) at baseline and after 6 months 2. Long term cognitive decline assessed using the Mini-Mental Status Examination (MMSE) to analyse the conversion to dementia up to 3 years _____ Previous secondary outcome measures as of 25/03/2020: 1. Cognition measured by reaction time and logical thinking assessments delivered and collected by the digital software at baseline and after 1, 2, 3, 4, 5 and 6 months, Mini-Mental Status Examination (MMSE) at baseline and after 6 months 2. Functional anatomical changes assessed by medical imaging techniques such as cMRT of the subgroup involved at baseline and 6 months 3. Long term cognitive decline assessed using the Mini-Mental Status Examination (MMSE) to analyze the conversion to dementia at 1, 2, 3, 4 and 5 years _____ Previous secondary outcome measures as of 18/03/2020: 1. Cognition measured by reaction time and logical thinking assessments delivered and collected by the digital software at baseline and after 1, 2, 3, 4, 5 and 6 months, Mini-Mental Status Examination (MMSE) at baseline and after 6 months 2. Non-cognitive symptoms measured by a self-created instrument based on the Neuropsychiatric Inventory and the Mild Behavioral Impairment Checklist 3. Functional anatomical changes	—

Measure

Time frame

Current secondary outcome measures as of 14/12/2020: 1. Cognition measured by reaction time and logical thinking assessments delivered and collected by the digital software at baseline and after 1, 2, 3, 4, 5 and 6 months and by the Mini-Mental Status Examination (MMSE) at baseline and after 6 months Exploratory outcome measures: Long-term cognitive status assessed using the Montreal Cognitive Assessment (MoCA) and the Mini-Mental Status Examination (MMSE), yearly in the open phase _____ Previous secondary outcome measures as of 23/06/2020: 1. Cognition measured by reaction time and logical thinking assessments delivered and collected by the digital software at baseline and after 1, 2, 3, 4, 5 and 6 months, Mini-Mental Status Examination (MMSE) at baseline and after 6 months 2. Long term cognitive decline assessed using the Mini-Mental Status Examination (MMSE) to analyse the conversion to dementia up to 3 years _____ Previous secondary outcome measures as of 25/03/2020: 1. Cognition measured by reaction time and logical thinking assessments delivered and collected by the digital software at baseline and after 1, 2, 3, 4, 5 and 6 months, Mini-Mental Status Examination (MMSE) at baseline and after 6 months 2. Functional anatomical changes assessed by medical imaging techniques such as cMRT of the subgroup involved at baseline and 6 months 3. Long term cognitive decline assessed using the Mini-Mental Status Examination (MMSE) to analyze the conversion to dementia at 1, 2, 3, 4 and 5 years _____ Previous secondary outcome measures as of 18/03/2020: 1. Cognition measured by reaction time and logical thinking assessments delivered and collected by the digital software at baseline and after 1, 2, 3, 4, 5 and 6 months, Mini-Mental Status Examination (MMSE) at baseline and after 6 months 2. Non-cognitive symptoms measured by a self-created instrument based on the Neuropsychiatric Inventory and the Mild Behavioral Impairment Checklist 3. Functional anatomical changes

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Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 18, 2026