Mental and behavioural disorder Mental and Behavioural Disorders Subtance abuse
Conditions
Interventions
The experimental treatment (MI plus CBT) will consist of motivational interviewing to increase motivation to reduce substance use
CBT for help with both substance use reduction and symptom management
and relapse prevention strategies. Patients randomised to receive MI plus CBT will be offered up to 26 sessions over 12 months with treatment being located at home or clinic according to the patient's
Sponsors
University of Manchester (UK)
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnostic and Statistical Manual of Mental Disorders, Fourth edition (DSM IV) diagnostic criteria for schizophrenia, schizophreniform or schizoaffective disorder 2. Recorded contact and treatment from mental health services at the point of recruitment 3. Prescribed anti-psychotic medication 4. Alcohol use exceeding 28 units for males, 21 units for females on at least half the weeks in the previous 3 months 5. DSM IV diagnosis of drug and/or alcohol dependence or abuse 6. No significant history of organic factors implicated in the aetiology of psychotic symptoms 7. English speaking 8. Informed patient consent 9. Having a fixed abode
Exclusion criteria
Exclusion criteria: See inclusion criteria
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Added as of 6 February 2007: Measures of symtomatology, relapses, substance misuse and health economic analyses. | — |
Primary
| Measure | Time frame |
|---|---|
| Either readmission to hospital for reason related to psychosis or death from any cause/not admitted to hospital in the 12 month post-treatment period. | — |
Countries
United Kingdom
Outcome results
None listed