Deep-inspirational breath hold during breast radiotherapy

Deep-Inspirational Breath-Hold (DIBH) technique in Left-sided Breast Cancer: individual decision-making is needed on its use

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14360721

Enrollment

150

Registered

2021-02-12

Start date

2018-01-23

Completion date

Unknown

Last updated

2023-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Left breast cancer needing adjuvant radiotherapy Cancer Malignant neoplasm of breast

Interventions

Conventional radiotherapy is used with the DIBH technique, and doses to the normal tissues, risk organs are analyzed in comparison to that if DIBH is not practised (free-breathing supine or if the pat

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients >18 years old who have left-sided breast cancer 2. Eligible for postoperative radiotherapy 3. No comorbidity that could prevent practising DIBH (bronchial asthma, obesity, hypacusis etc)

Exclusion criteria

Exclusion criteria: Presence of COPD, bronchial asthma or another severe comorbidity that would hinder cooperation during DIBH (extreme obesity, mental disorder, hypacusis)

Design outcomes

Primary

Measure	Time frame
Heart and LAD doses measured using dosimetry data extracted from radiotherapy plans at the time of treatment planning, before the start of the individuals' radiotherapy, and analyzed both individually before the radiotherapy and later on as a database after the last patient's radiotherapy. Dosimetry data analyzed individually whether the target dose constraints were achieved or not, and as a database using statistical methods (repeated ANOVA test and paired t-test).	—

Measure

Time frame

Heart and LAD doses measured using dosimetry data extracted from radiotherapy plans at the time of treatment planning, before the start of the individuals' radiotherapy, and analyzed both individually before the radiotherapy and later on as a database after the last patient's radiotherapy. Dosimetry data analyzed individually whether the target dose constraints were achieved or not, and as a database using statistical methods (repeated ANOVA test and paired t-test).

—

Secondary

Measure	Time frame
Lung, breast/chest wall and lymph node doses measured using dosimetry data extracted from radiotherapy plans at the time of treatment planning, before the start of the individuals' radiotherapy, and analyzed both individually before the radiotherapy and later on as a database after the last patient's radiotherapy. Dosimetry data were analyzed individually whether the target dose constraints were achieved or not, and as a database using statistical methods (repeated ANOVA test and paired t-test).	—

Measure

Time frame

Lung, breast/chest wall and lymph node doses measured using dosimetry data extracted from radiotherapy plans at the time of treatment planning, before the start of the individuals' radiotherapy, and analyzed both individually before the radiotherapy and later on as a database after the last patient's radiotherapy. Dosimetry data were analyzed individually whether the target dose constraints were achieved or not, and as a database using statistical methods (repeated ANOVA test and paired t-test).

—

Countries

Hungary

Contacts

Public ContactZsuzsanna Kahán

kahan.zsuzsanna@med.u-szeged.hu+36 (0)70 3311585

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 22, 2026