End-stage renal failure Urological and Genital Diseases
Conditions
Interventions
This is a prospective, blinded, observational study. Patients undergoing intermittent haemodialysis will be imaged using echocardiography, lung ultrasonography, femoral vein and intra-abdominal ultras
Sponsors
King's College Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged =18 years old 2. Presenting for intermittent haemodialysis 3. In excess of dry weight prior to the dialysis session
Exclusion criteria
Exclusion criteria: Previous echocardiographic evidence of right heart dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The efficacy of a novel ultrasound score (VEXUS) in detecting changes in venous congestion during fluid removal in patients undergoing intermittent haemodialysis measured using ultrasonography, femoral vein and intra-abdominal ultrasound at three-time points during the dialysis session | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Changes in selected lung ultrasound parameters during fluid removal in patients undergoing intermittent haemodialysis 2. Changes in femoral vein Doppler signal during fluid removal in patients undergoing intermittent haemodialysis Variables measured/obtained using ultrasound – left ventricular function and size (VTi, quantitative), right ventricular function and size, IVC diameter and collapsibility, hepatic vein flow profile, portal vein flow profile, VEXUS score, lung ultrasound score, femoral vein flow profile. The patient’s blood pressure and heart rate were recorded. These measures were performed at the start, middle and end of the dialysis session. We obtained the aetiology/cause of their renal failure, target dry weight from the medical records | — |
Countries
England, United Kingdom
Contacts
Public ContactAdrian Wong
Outcome results
None listed