Bladder cancer Cancer Malignant neoplasm of bladder
Conditions
Interventions
Intervention: Pre-operative intravesical instillation of solution of hexylaminolevulinic acid (HAL) - photodynamic 'bluelight' assisted resection of bladder tumours
Control: Conventional 'whitelight'
Sponsors
Guy's Hospital - Research and Development Department (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. New diagnosis of bladder tumour - the study is designed to reduce recurrence rates in newly diagnosed cases of bladder tumours 2. Superficial disease - the study will address the recurrence rates in superficial bladder cancer 3. No history of previous bladder surgery - previous surgical procedures to the bladder may cause artifactual changes when using 'blue light' cystoscopy 4. Life expectancy of at least 1-year - study duration will be for 1-year
Exclusion criteria
Exclusion criteria: 1. Previous bladder tumour or coexisting/previous upper tract disease - the study is designed to reduce recurrence rates in newly diagnosed cases of bladder tumours 2. Muscle invasive disease - the study will address the recurrence rates in superficial bladder cancer 3. Previous bladder surgery -previous surgical procedures to the bladder may cause artifactual changes when using 'blue light' cystoscopy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rates of bladder tumour at 3 months and 12 months post surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of histology | — |
Countries
United Kingdom
Outcome results
None listed