Chronic kidney disease peritoneal dialysis patients Urological and Genital Diseases
Conditions
Interventions
From March 2020 to February 2022, 52 patients with chronic kidney failure (CRF) who received moxibustion combined with peritoneal dialysis (PD) in our hospital (moxibustion group) and 50 patients with
Sponsors
Shanghai Sixth People's Hospital Jinshan Branch
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged > 18 years old; 2. Clinical diagnosis of CRF with specific indications for PD.
Exclusion criteria
Exclusion criteria: 1. Decreased peritoneal clearance rate caused by various abdominal lesions; 2. Within 3 days of abdominal surgery and no complete healing of the wound, which could easily lead to dialysate leaks; 3. Localized inflammatory lesions in the peritoneum, which could be spread by PD; 4. Late pregnancy or large intra-abdominal tumors, which could result in reduced abdominal volume and subsequent unsatisfactory effect of PD; 5. Extensive abdominal wall infection or severe burns, which could cause failure of intubation; 6. Intra-abdominal vascular diseases, such as polyangiitis, severe arteriosclerosis, scleroderma, which could reduce the dialysis efficacy; 7. Severe respiratory insufficiency; in such patients, excessive fluid intake would aggravate respiratory insufficiency, and if the patients were still required to receive PD, fluid intake was less; 8. Long-term insufficiency of protein and caloric intake; such patients were not suitable for PD because PD could lead to daily loss of protein more than 6 g
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. After 12 weeks of treatment, gastrointestinal function was analyzed by blood tests of secretion of gastrin, motilin, cholecystokinin, somatostatin and growth hormone releasing peptide before and after treatment. 2. Fecal samples were collected 12 weeks after treatment for 16S rDNA analysis to observe changes in fecal microbial characteristics | — |
Secondary
| Measure | Time frame |
|---|---|
| Renal function index: After 12 weeks of treatment, Blood routine markers and blood electrolytes were detected by blood. Routine biochemical parameters and 24-hour urinary protein quantification (UPQ) by urine testing | — |
Countries
China
Contacts
Public ContactKun Liu
Outcome results
None listed