Replacing some of the starch in the diet with fibre to manage blood glucose levels in those with type 2 diabetes.

Carbohydrate in the diet. A starch exchange model for managing glycaemia in type 2 diabetes.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN14165221

Enrollment

Registered

2019-04-03

Start date

2019-06-01

Completion date

Unknown

Last updated

2026-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes Nutritional, Metabolic, Endocrine

Interventions

Participants will consume either diet 1 or diet 2 for 4 consecutive days. Control diet is “diet 1” and will include 50% carbohydrate comprising standard starch versions of bread, pasta and snack crack

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with a diagnosis of type 2 diabetes > 6 months 2. Males and females 3. 18-70 years 4. Access to a kitchen 5. Ability to understand English (to provide informed consent)

Exclusion criteria

Exclusion criteria: 1. Use of insulin and GLP-1 analogues 2. History of gastroperesis or gastric surgery 3. Coeliac disease/wheat intolerance 4. Irritable bowel syndrome 5. HbA1c >75 mmol/mol 6. Pregnancy/breastfeeding 7. Excess alcohol intake 8. Glucose-lowering drug dosage adjustment within the previous month

Design outcomes

Primary

Measure	Time frame
Postprandial glucose (MAGE) excursion resulting from consumption of both diets. The MAGE calculation will be made by measuring the arithmetic mean of the difference between consecutive peaks and nadirs. Blood glucose will be measured continuously; however, time points of interest are the following: 8.15 am-9.00 am (post breakfast), 10.30 am-11.15 am (post snacks), 12 pm-12.45 pm (post lunch), 6.00 pm-6.45 pm (post dinner).	—

Measure

Time frame

Postprandial glucose (MAGE) excursion resulting from consumption of both diets. The MAGE calculation will be made by measuring the arithmetic mean of the difference between consecutive peaks and nadirs. Blood glucose will be measured continuously; however, time points of interest are the following: 8.15 am-9.00 am (post breakfast), 10.30 am-11.15 am (post snacks), 12 pm-12.45 pm (post lunch), 6.00 pm-6.45 pm (post dinner).

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Secondary

Measure	Time frame
1. Peak postprandial glucose excursion after meals 2. The time to peak postprandial glucose excursion 3. Mean blood glucose 4. The standard deviation of blood glucose 5. 24-hour glucose area under the curve (AUC). Blood glucose will be measured continuously; however, time points of interest are the following: 8.15 am-9.00 am (post breakfast), 10.30 am-11.15 am (post snacks), 12 pm-12.45 pm (post lunch), 6.00 pm-6.45 pm (post dinner).	—

Measure

Time frame

1. Peak postprandial glucose excursion after meals 2. The time to peak postprandial glucose excursion 3. Mean blood glucose 4. The standard deviation of blood glucose 5. 24-hour glucose area under the curve (AUC). Blood glucose will be measured continuously; however, time points of interest are the following: 8.15 am-9.00 am (post breakfast), 10.30 am-11.15 am (post snacks), 12 pm-12.45 pm (post lunch), 6.00 pm-6.45 pm (post dinner).

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Countries

England, United Kingdom

Contacts

Public ContactSineaid Collins

s.m.collins@surrey.ac.uk+44(0)1483 686993

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: May 22, 2026