Change in disability in activities of daily living over time among adults with advanced respiratory disease during the COVID-19 pandemic

Comparing disability in activities of daily living over time among adults with advanced lung cancer or respiratory disease during the COVID-19 pandemic

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN14159936

Enrollment

120

Registered

2020-12-14

Start date

2020-03-01

Completion date

Unknown

Last updated

2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exploring disability in patients with non-small cell lung cancer or respiratory disease Respiratory

Interventions

Sample: advanced no small cell cancer or respiratory disease Recruitment sites: hospital lung cancer and respiratory inpatients and outpatient clinics

hospice/palliative care inpatients, outpatients, or community teams. Outcome variable: disability in activities of daily living Explanatory variables: symptom burden

assistive device use

social isolation Outcome measures: Barthel Index

Lawton Brody IADL scale

WHO Disability Assessment Scale (WHODAS 2.0)

Palliative Outcomes Scale-Symptoms

Chronic Disease Self-Efficacy Social Support Sub-scale Data collection: Baseline self-reported questionnaire via telephone and monthly postal survey for 6 months or until death.

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged >18 years 2. Advanced lung cancer or respiratory disease as defined by one of the following: 2.1. Lung cancer: Inoperable stage III or IV non-small cell lung cancer 2.2. Chronic Obstructive Lung Disease (COPD): Severe or very severe stages of COPD according to the criteria set by the Global Initiative for Chronic Obstructive Lung Disease (GOLD): stage III (FEV1/FVC 1 month as assessed by the person taking consent

Exclusion criteria

Exclusion criteria: 1. Patients aged <18 years 2. Patients who lack the capacity to consent 3. Patients who lack the ability to understand and complete a questionnaire in English 4. Life expectancy of <1 month as assessed by the person taking consent

Design outcomes

Primary

Measure	Time frame
Disability (independence) in basic activities of daily living measured using the Barthel Index at baseline and monthly for 6 months	—

Secondary

Measure	Time frame
1. Disability (independence) in instrumental activities of daily living measured using the Lawton Brody IADL scale at baseline and monthly for 6 months 2. Disability severity in activities of daily living measured using the WHO Disability Assessment Scale (WHODAS 2.0) at baseline and monthly for 6 months 3. Symptom burden measured using the Palliative Outcomes Scale-Symptoms (POS-S) at baseline and monthly for 6 months 4. Confidence to receive social support measured using the Chronic Disease Self-Efficacy Social Support Sub-scale at baseline	—

Measure

Time frame

1. Disability (independence) in instrumental activities of daily living measured using the Lawton Brody IADL scale at baseline and monthly for 6 months 2. Disability severity in activities of daily living measured using the WHO Disability Assessment Scale (WHODAS 2.0) at baseline and monthly for 6 months 3. Symptom burden measured using the Palliative Outcomes Scale-Symptoms (POS-S) at baseline and monthly for 6 months 4. Confidence to receive social support measured using the Chronic Disease Self-Efficacy Social Support Sub-scale at baseline

—

Countries

England, United Kingdom

Contacts

Public ContactLucy Fettes

lucy.fettes@kcl.ac.uk+44 (0)7854607441

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026