Clinical Assessment Study of the HAnd (CASHA) - 6-year follow-up

The course of hand pain, hand problems and hand osteoarthritis in community-dwelling adults aged 50 years and over: the 6-year follow-up of the Clinical Assessment Study of the Hand (CASHA)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN14121394

Enrollment

475

Registered

2012-07-03

Start date

2011-09-26

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal, All Diseases Musculoskeletal Diseases Polyarthrosis, unspecified

Interventions

Seven plain x-rays will be taken of the hands and knees as follows: dorsi-palmar views of each hand and wrist, weight-bearing semiflexed posteroanterior (PA) view of both knees, and lateral and skylin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Existing member of the CAS-HA cohort 2. Responded to the 3-year Follow-up Health Questionnaire 3. Provided written informed consent to further contact at 3-year follow-up stage 4. Male & female participants 5. Lower Age Limit 50 years

Exclusion criteria

Exclusion criteria: 1. Participants who have died since 3-year follow-up 2. Participants who have become vulnerable (e.g. participants with known new-onset dementia, serious/terminal pathology) since their baseline assessment as judged by the lead GP at each practice 3. Participants who have withdrawn consent to further contact following the 3-year follow-up We are keen to avoid upsetting or burdening participants and their relatives whose circumstances may have changed. Prior to any contacts being made for 6-year follow-up we will check to ensure that the mailing list contains no participants who have died. This means checking the mailing list at each practice. We are also including a screen of the mailing list by the lead GP at each practice to identify and exclude those participants who have become vulnerable since the screen was last conducted.

Design outcomes

Primary

Measure	Time frame
Australian Canadian Hand Osteoarthritis Index (AUSCAN) measured at baseline	—

Secondary

Measure	Time frame
1. Anxiety and depression (HADS) measured at baseline 2. Current employment status measured at baseline 3. General health (SF-12) measured at baseline 4. Pain location (manikin) measured at baseline 5. Presence of hand pain and problems nodes, swelling, and participation restriction measured at baseline 6. Radiographic hand osteoarthrits (OA) measured at baseline 7. Radiographic knee OA measured at baseline 8. Symptom satisfaction measured at baseline	—

Measure

Time frame

1. Anxiety and depression (HADS) measured at baseline 2. Current employment status measured at baseline 3. General health (SF-12) measured at baseline 4. Pain location (manikin) measured at baseline 5. Presence of hand pain and problems nodes, swelling, and participation restriction measured at baseline 6. Radiographic hand osteoarthrits (OA) measured at baseline 7. Radiographic knee OA measured at baseline 8. Symptom satisfaction measured at baseline

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Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026