Chest pain Circulatory System
Conditions
Interventions
Copeptin is measured in patients with chest pain lasting up to 6h at admission and remains double-blinded throughout the enrollment. Further all patients undergo routine management for the condition b
Sponsors
Silesian Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Chest pain lasting five minutes or more 2. Beginning of symptoms in last six hours before admission
Exclusion criteria
Exclusion criteria: 1. ST-segment elevation myocardial infarction (STEMI) 2. End-stage renal insufficiency (defined as GFR <15 ml/min/1.73m2 and/or dialysis) 3. Anemia (defined as level of hemoglobin <10 g/dl for men; <8 g/dl for women) 4. Hyponatremia (defined as level of Na+ <125mmol/l) 5. Injury or big surgery in last four weeks 6. Cancer with predicted life duration < six months 7. Pregnancy 8. Age < 18 years 9. Lack of informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Primary diagnostic endpoint is the final diagnosis of NSTEMI 2. Primary prognostic endpoint is death of cardiovascular origin | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Secondary diagnostic endpoint is the diagnosis of ACS (NSTEMI+UA) 2. Secondary prognostic endpoints is as Major Adverse Cardiac and Cerebrovascular Events (MACCE) and included death of cardiovascular origin, non-fatal AMI, UA, repeated cardiac revascularization, stroke | — |
Countries
Poland
Outcome results
None listed