Treatment for periodontal diseases in type 2 diabates patients Oral Health
Conditions
Interventions
The control group received non-surgical periodontal treatment and oral physiotherapy for 30 days (n = 19). The experimental group received non-surgical periodontal treatment plus 50 mg of zinc glucon
Sponsors
Universidad Veracruzana
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with periodontal diseases associated with type 2 diabetes mellitus 2. Males and females 3. Aged 18-60 years 4. Accepted to participate in the research 5. Patients under medical surveillance 6. Patients who attended the periodontia service at an established time period
Exclusion criteria
Exclusion criteria: 1 Patients with hypersensitive to zinc and magnesium supplements 2. Patients with prior non-surgical periodontal treatment 3. Patients who consumed antibiotics, steroids, and central nervous system (CNS) depressants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Clinical periodontal parameters such as deep on probing, clinical attachment level, bleeding on probing, and periodontal inflamed surface area, measured using periodontogram at baseline and 30 days after treatment 2. Biochemical parameters such as glucose levels, zinc levels, magnesium levels, total cholesterol levels, triglycerides levels, HDL-C, and LDL-C, measured using biochemical analyses at baseline and 30 days after non-surgical periodontal treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Oxidative stress measured using lipoperoxidation reaction and MDA levels at baseline (day 0) and 30 days after the interventions 2. Antioxidant enzymes measured using commercial kits (superoxide dismutase and catalase levels) at baseline (day 0) and 30 days after the interventions | — |
Countries
Mexico
Outcome results
None listed