Infants undergoing MRI scanning with dexmedetomidine sedation Not Applicable
Conditions
Interventions
Children < 3 years old scheduled for short (<45 minutes) MRI procedures with dexmedetomidine sedation may be included. In the researchers' department, children are routinely fasted for at least 4 hour
Sponsors
Uppsala University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Infants planned for an MRI scan
Exclusion criteria
Exclusion criteria: 1. Age 36 months 3. Gastro-esophageal reflux disease 4. Respiratory disease such as bronchopulmonary dysplasia, requiring oxygen therapy or CPAP 5. Congenital heart disease with cyanosis or myocardial dysfunction 6. MRI protocol planned duration > 45 minutes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI scan outcome (with or without movement artefacts) when the patient is moved from the MRI suite after the scanning procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Duration of MRI scanning procedure, the time from the patient is laid onto the MRI scanner bed until the patient is taken off the bed after the completed scan 2. Incidence of movements during the procedure, the number of times the MRI scanning is stopped due to observed movements of the patients or movement artefacts on the MRI scan preview. Each movement event is recorded on the CRF when it occurs and summed at the end of the procedure 3. Complications of the procedure 4. The volume of residual gastric volume content after bottle feeding 1-4 hours prior to scanning is measured by delineating the gastric mucosa on adjacent MRI images covering the full extent of the stomach and calculating the volume in millilitres by summing the resulting voxels. An estimate of gastric emptying rate is calculated by integrating the sets of ingested volume VOIs subtracted by the residual volume vs time between ingestion and the start of scanning of the stomach | — |
Countries
Sweden
Outcome results
None listed