Hypertension Circulatory System Hypertension
Conditions
Interventions
Two treatment groups:
1. Placebo
2. Indapamide Sustained Release (SR) 1.5 mg plus perindopril 2 - 4 mg if required.
Goal: diastolic blood pressure less than 80 mmHg with systolic pressure less than 1
Sponsors
British Heart Foundation (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. People 80 years old and above 2. Sustained systolic pressure 160 - 199 mmHg and diastolic (phase V) pressure 90 - 109 mmHg 3. No evidence of renal failure or co-morbidity requiring anti-hypertensive treatment
Exclusion criteria
Exclusion criteria: Does not comply with above inclusion criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stroke events (fatal and non-fatal). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Total mortality 2. Cardiovascular mortality 3. Cardiac mortality 4. Stroke mortality 5. Skeletal fracture | — |
Countries
United Kingdom
Outcome results
None listed