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ICONS II: Identifying Continence OptioNs after Stroke

ICONS II: Identifying Continence OptioNs after Stroke randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN14005026
Enrollment
818
Registered
2018-02-19
Start date
2018-05-01
Completion date
Unknown
Last updated
2022-08-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adults with stroke and urinary incontinence Nervous System Diseases Stroke and urinary incontinence

Interventions

Participants who fulfil the eligibility criteria and have consented and completed their baseline questionnaire are randomised to either the intervention group or usual care group. Randomisation (1:1
moderate: 6-12
severe or very severe: 13-21
catheterised) using blocks of random length. The random allocation procedure is delivered using the secure remote web-based system provided by the Lancashire Clinical Trials Unit. INT
a bladder scan to estimate post-void residual urine volume
and identification of the type of incontinence (stress UI: any response other than ‘never’ to the Leicester Urinary Symptom Questionnaire (LUSQ) question “Do you ever leak when you do any of the foll
urge UI: the response ‘most of the time’, ‘sometimes’ or ‘occasionally’ to the LUSQ question “When you get the urge to pass urine, does any leak before you get to the toilet?”
mixed UI: both stress and urge UI
‘functional’ UI, defined as mobility or balance restrictions stopping patients reaching the toilet on time). The inte

Sponsors

University of Central Lancashire
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adult patients aged 18 and older with: 1.1. Acute stroke 1.2. UI (at least one episode within a 24 hour period) OR an indwelling urethral catheter 1.3. NIH Stroke Scale level of consciousness 0-2

Exclusion criteria

Exclusion criteria: 1. Long-term indwelling urethral catheter pre-stroke 2. Subdural or subarachnoid haemorrhage

Design outcomes

Primary

MeasureTime frame
Severity of incontinence is measured using the International Consultation on Incontinence Questionnaire–Urinary Incontinence-Short Form (ICIQ-UI-SF ) total score at baseline, discharge from the stroke unit, 3 months (primary endpoint) and 6 months post-randomisation.

Secondary

MeasureTime frame
1. Number of days with indwelling urethral catheter in situ measured using patient notes at discharge from the stroke unit, and patient/consultee report at 3 and 6 months post-randomisation 2. Number of urinary tract infections measured using patient notes at discharge from the stroke unit, and patient/consultee report at 3 and 6 months 3. Urinary symptoms measured using the Leicester Urinary Symptom Questionnaire (LUSQ), questions “Do you ever leak when you do any of the following?” and “When you get the urge to pass urine, does any leak before you get to the toilet?” only) at baseline, 3 and 6 months 4. Functional ability measured using the Barthel Index at baseline, 3 and 6 months 5. Quality of life measured using the EuroQol (EQ-5D-5L) at baseline, 3 and 6 months 6. Incontinence-specific quality of life measured using the Incontinence Quality of Life Instrument (IQoL) at 3 and 6 months 7. Falls measured using adverse event reports at discharge from the stroke unit, and patient/consultee report at 3 and 6 months 8. Death measured using adverse event reports at discharge from the stroke unit, and by General Practitioner notification at 3 and 6 months

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 12, 2026