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Effect of XP-endo finisher on microbial root canal flora after using multiple irrigation protocols

A comparative study of several final irrigation protocols and the use of XP-endo finisher in changing of the microbial root canal flora

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN13986591
Enrollment
60
Registered
2025-04-28
Start date
2022-01-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with necrotic pulp Oral Health

Interventions

Root canal treatment. The study samples (both clinical and laboratory) were divided into six groups: Groups 1 and 2: Irrigation was performed using 5.25% sodium hypochlorite with and without the XP-en

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients medically free from any systemic diseases 2. Patients between the age group of 20 and 40 years old 3. Absence of preoperative pain 4. Necrotic cases only 5. Presence of periapical radiolucency 1-5 mm in diameter 6. No antibiotics in the past three months

Exclusion criteria

Exclusion criteria: 1. Teeth with symptomatic irreversible pulpitis 2. Teeth with open apices 3. Consumption of any type of antibiotics in the past three months 4. Systemic diseases 5. Pregnant and lactating females

Design outcomes

Primary

MeasureTime frame
To compare the bacterial count before and after clinical root canal preparation using three final irrigation protocols: 1. Sodium hypochlorite (NaOCl) alone 2. Sodium hypochlorite combined with chlorhexidine (CHX) 3. Sodium hypochlorite combined with QMiX

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

Syria

Contacts

Public ContactFarah;Farah Estefane;Estefane

;

farah3.estefan@damascusuniversity.edu.sy;estefanfarah3@gmail.com+963 988704477;+963 988704477

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026