Optimal extraction incision placement in retroperitoneal laparoscopic living donor nephrectomy. Digestive System
Conditions
Interventions
This prospective, single-blind RCT involved living kidney donors who were randomized 1:1 to an abdominal diagonal or a lumbar horizontal extraction incision.
Randomization and Blinding
Participants w
right-sided donations were excluded during screening (see Participant Selection). The allocation sequence was generated by an independent statistician and concealed using sequentially numbered, opaque
Sponsors
First Affiliated Hospital of Henan University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 65 years 2. Body mass index (BMI) between 18.5 and 29.9 kg/m². The BMI upper limit of 29.9 kg/m² was selected to minimize confounding from obesity-related complications such as hernia and wound healing issues, while maintaining generalizability. 3. Estimated glomerular filtration rate greater than 80 mL/min/1.73m² 4. American Society of Anesthesiologists (ASA) physical status classification I or II
Exclusion criteria
Exclusion criteria: 1. Previous major abdominal or retroperitoneal surgery 2. Known abdominal wall hernia or significant diastasis recti, chronic pain syndromes requiring regular analgesic use 3. Neuromuscular disorders affecting abdominal wall function 4. Active psychiatric conditions that could impact pain perception or reporting 5. Pregnancy or plans for pregnancy within the study period 6. Any contraindication to retroperitoneal laparoscopic surgery 7. Donors with variant renal anatomy requiring extensive dissection or those requiring right-sided nephrectomy were excluded to maintain procedural homogeneity 8. Right-sided nephrectomies were excluded to maintain procedural homogeneity and minimize anatomical variability, as the right kidney presents distinct surgical challenges
Countries
China
Contacts
Public ContactKaixuan Wang
Outcome results
None listed