Mood [affective] disorders Mental and Behavioural Disorders
Conditions
Interventions
None listed
Sponsors
University of Bristol
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Aged =18 years 2. Have a BDI-II score =14 3. Meet ICD-10 depression criteria 4. Are willing to discuss past stressful experiences related to their depression
Exclusion criteria
Exclusion criteria: 1. Have a diagnosis of PTSD/complex PTSD 2. Have a substance use disorder (including alcohol dependence) within the last 12 months 3. Have bipolar disorder, schizophrenia or psychosis 4. *Have a current diagnosis of moderate/severe personality disorder 5. Have a dissociative disorder 6. Have dementia 7. Are currently under secondary care for depression (including those referred but not yet seen) at eligibility screening 8. *Have a history of repeated contacts with secondary care services or community mental health teams 9. *Have a history of repeated self-harm 10. Are currently receiving psychotherapy for depression at eligibility screening 11. Unable to complete self-administered questionnaires in English 12. Taking part in another trial of an intervention for mental health *Criteria at the discretion of the clinical PI, who will use their judgement in deciding if the patient should be excluded based on these factors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depressive symptoms will be measured using the Beck Depression Inventory (BDI-II) as a continuous variable at 26 weeks post-randomisation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Proportional change in depressive symptoms will be measured using the Beck Depression Inventory-II (BDI-II) at 26 and 52 weeks post-randomisation 2. Remission of depressive symptoms (BDI-II < 10) will be measured using the Beck Depression Inventory-II (BDI-II) at 26 and 52 weeks post-randomisation 3. Symptoms of depression will be measured using the Patient Health Questionnaire-9 (PHQ-9) at 26 and 52 weeks post-randomisation 4. Symptoms of anxiety will be measured using the Generalized Anxiety Disorder-7 (GAD-7) at 26 and 52 weeks post-randomisation 5. Impairment in functioning will be measured using the Work and Social Adjustment Scale (WSAS) at 26 and 52 weeks post-randomisation 6. Quality of life will be measured using the EuroQol five-dimension five-level scale (EQ-5D-5L) at 26 and 52 weeks post-randomisation 7. Capability will be measured using the ICEpop CAPability measure for Adults (ICECAP-A) at 26 and 52 weeks post-randomisation 8. Continuous score on the Beck Depression Inventory-II (BDI-II) will also be measured at 52 weeks post-randomisation Data on PHQ-9 and GAD-7 will also be collected as part of the brief follow-ups at 2, 8, 16 & 39 weeks | — |
Countries
England, United Kingdom
Contacts
Public ContactLeonora Cotton
Outcome results
None listed