Breast Cancer Cancer Malignant neoplasm of breast
Conditions
Interventions
Data and Tissue Collection After Enrolment
After written consent is given and after patient has been enrolled in the study the data should be entered into the database (from retrospect
Sponsors
University of Liverpool
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 16 years of age or above 2. Histologically and/or cytologically confirmed breast cancer with CNS involvement, as defined as having one or more of the following: 2.1. Metastases to the brain parenchyma 2.2. Metastases to the leptomeninges 2.3. Paraneoplastic Neurological Disorders 3. FFPE of biopsied or resected primary breast cancer, non-CNS metastasis and/ or brain metastasis is available or will be available. 4. Informed consent
Exclusion criteria
Exclusion criteria: 1.Unable to comply with study procedures or give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical staff will be collecting information onto eCRFs (REDCap) at registration (1st or 2nd Visit), CSF Extraction Visit, Imaging/ Scan Visit, Disease Progression Visit: 1. Disease history and characteristics 2. Prior cancer therapy (top line) 3. Current anti-cancer treatment and concomitant medications Progression Details | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
United Kingdom
Outcome results
None listed