The usefulness of vacuum-assisted closure therapy in postoperative abdominal wound dehiscence

Assessing the effect of vacuum-assisted closure therapy in postoperative abdominal wound dehiscence: an observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN13921883

Enrollment

Registered

2020-05-31

Start date

2017-08-10

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative abdominal wound dehiscence Surgery

Interventions

The data, including wound type, size for each patient are collected in a standardized manner. Then under sterile conditions, adequate debridement and saline irrigation are done followed by paraffin-im

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who underwent VAC. therapy for sheath dehiscence developed in the postoperative period between 2017 to 2019 2. Patients above 18 years of age including both males and females

Exclusion criteria

Exclusion criteria: 1. Patients who had only skin dehiscence 2. Postoperative ascites 3. Bile leak 4. Entero cutaneous fistulas 5. Metastatic carcinoma 6. Multi-organ dysfunction 7. Critically ill patients on a ventilator 8. Those who needed further exploration

Design outcomes

Primary

Measure	Time frame
1. Duration for achieving a cutaneous cover or granulation tissue without any local sepsis: 1.1. Cutaneous cover: the time (days) from the day of VAC application until the wound is covered with skin grafting or secondary suturing or by secondary intion of healing 2.2. Granulation tissue appearance and no local sepsis: the day when there is no or minimal pus discharge with healthy red granulation tissue appearance after the 1st VAC application. A macroscopic objective observed after each VAC application 2. Duration of hospital stay, measured using medical records as the time (days) between the 1st VAC application until discharge from the hospital	—

Measure

Time frame

1. Duration for achieving a cutaneous cover or granulation tissue without any local sepsis: 1.1. Cutaneous cover: the time (days) from the day of VAC application until the wound is covered with skin grafting or secondary suturing or by secondary intion of healing 2.2. Granulation tissue appearance and no local sepsis: the day when there is no or minimal pus discharge with healthy red granulation tissue appearance after the 1st VAC application. A macroscopic objective observed after each VAC application 2. Duration of hospital stay, measured using medical records as the time (days) between the 1st VAC application until discharge from the hospital

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Secondary

Measure	Time frame
1. Total leukocyte counts measured with a routine complete blood picture before 1st VAC and after the 2nd VAC 2. Wound size measured with a standard scale before and after application of VAC 3. Amount of negative pressure applied: the average amount of negative pressure (mmHg) applied for each patient measured after the last VAC 4. Total sessions of VAC dressings required: each VAC dressing is noted in the record and the total sessions of dressings applied were noted at the time of discharge 5. Total cost of therapy: the cost applied for each VAC and total amount calculated after the end of last VAC 6. Incisional hernia measured clinically as well as by ultrasound during 6 months of follow up	—

Measure

Time frame

1. Total leukocyte counts measured with a routine complete blood picture before 1st VAC and after the 2nd VAC 2. Wound size measured with a standard scale before and after application of VAC 3. Amount of negative pressure applied: the average amount of negative pressure (mmHg) applied for each patient measured after the last VAC 4. Total sessions of VAC dressings required: each VAC dressing is noted in the record and the total sessions of dressings applied were noted at the time of discharge 5. Total cost of therapy: the cost applied for each VAC and total amount calculated after the end of last VAC 6. Incisional hernia measured clinically as well as by ultrasound during 6 months of follow up

—

Countries

India

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026