Diabetes Nutritional, Metabolic, Endocrine
Conditions
Interventions
People need to come to hospital for routine bloods which can often be difficult and painful. In this study we want to see if we can use blood obtained through finger prick method (similar to what peop
Sponsors
University of Leicester
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged >18 years of age 2. People with long-term conditions (LTC) (a subset will be consented separately for the feasibility phase) or healthy individuals attending UHL or primary care centres for routine bloods or assessments, e.g. elective surgery 3. Able to understand written and spoken English 4. Able to give informed consent 5. Participant agrees to have capillary and venous blood samples collected.
Exclusion criteria
Exclusion criteria: 1. Pregnant women with gestational diabetes or established diabetes 2. Those on dialysis or end stage renal disease (eGFR = 20mmol/l) 9.3. Splenectomy 9.4. Chronic alcohol intake of more than 14 units per week 9.5. Blood transfusion within past 12 weeks 9.6. Recent blood loss (< = 4 weeks) 9.7. Ribavirin and interferon-alpha use 9.8. Iron, B12 and folate deficiency anaemias
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Validation of capillary blood samples against venous samples: 1. HbA1c 2. Potassium 3. Sodium 4. Urea 5. Creatinine 6. Total Cholesterol 7. Low Density Lipoprotein (LDL) – Cholesterol 8. High Density Lipoprotein (HDL) – Cholesterol 9. Triglyceride (TG) 10. ALT (Alanine Aminotransferase) 11. CRP 12. TSH (Thyroid Stimulating Hormone) Validation Phase: Months 1 – 12 Feasibility Phase: Months 13 - 18 | — |
Secondary
| Measure | Time frame |
|---|---|
| Feasibility outcomes measured in months 13 - 18 1. Service User experience: Surveys and interviews 2. Adherence rate: Proportion of responders returning the remote samples. 3. Cost-effectiveness analysis: Compared to standard venous samples | — |
Countries
England, United Kingdom
Outcome results
None listed