Non contact lens wearers that suffer from dry eye Eye Diseases
Conditions
Interventions
Participants will complete a dry eye evaluation by a qualified optometrist and also answer some questions about their dry eye. They will then have their corneal sensitivity assessed using a device cal
Sponsors
CooperVision International Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18 to 75 years; 2. No contact lens wear in the past 5 years. 3. Non-contact lens wearers divided into three groups based upon symptomatology: 3.1. Asymptomatic OSDI = 9.0 points 3.2. Symptomatic slight to mild OSDI >9.0 points & = 33.0 points 3.3. Symptomatic moderate to severe > 33 points 4. Best corrected visual acuity of at least 20/30 in each eye; 5. No history of eye surgery or ocular disease (except for dry eye) 6. No history of medical conditions which, in the investigator’s opinion, could impact ocular symptoms or corneal sensitivity. Examples include diabetes and autoimmune diseases. 7. No history of systemic or topical medication (except for artificial tears) which, in the investigator’s opinion, could impact symptoms or corneal sensitivity. Examples include acne medication, anti-inflammatory medication and/or dry eye medication; 8. Have read and understood the Participant Information Sheet in English; 9. Have read, signed and dated the Informed Consent.
Exclusion criteria
Exclusion criteria: 1. Ocular anterior segment infection, inflammation, abnormality, or active disease; 2. Monocular participants (only one eye with functional vision); 3. Any moderate or severe ocular condition observed during the slit lamp examination at the enrolment visit; 4. History of herpetic keratitis, ocular surgery or irregular cornea; 5. Known pregnancy or lactation during the study period; 6. Enrolment of the investigator or his/her staff, family members of the investigator, family members of the investigator’s staff, or individuals living in the households of these individuals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Corneal sensitivity is measured by the point at which a participant detects a light puff of air on their cornea. There are no defined time points for the measurement. | — |
Secondary
| Measure | Time frame |
|---|---|
| Extent of ocular symptoms measured by an OSDI questionnaire. | — |
Countries
England, United Kingdom
Contacts
Public ContactDeborah Moore
Outcome results
None listed