Cardiovascular disease in hemodialysis patients Circulatory System Cardiovascular disease in hemodialysis patients
Conditions
Interventions
Patients on chronic hemodialysis with glucose containing dialysis bath (contentration 5 mmol/L) continue their usual treatement for the initial four weeks of the study. Following this, the dialysis co
Sponsors
Norrlands University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adult patients (age > 18 years), no upper limit of age 2. Chronic dialysis treatment (patients with dialysis treatment more than three months) 3. All patients treated at the dialysis unit at Norrlands university hospital, Umeå, Sweden, who give informed consent and have no exclusion criterias
Exclusion criteria
Exclusion criteria: 1. Ongoing infection (elevated CRP) 2. Inability to understand information and give informed consent 3. Patients with diabetes mellitus prone to hypoglycemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin autofluorescence is measured using the AGE Reader (DiagnOptics Technologies BV, Groningen, The Netherlands) at baseline, 1 and 2 weeks after dialysate is switched to glucose free dialysate. | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma autofluorescence is measured using a Tecan Genios microplate reader (Tecan Group Ltd., Männedorf, Switzerland) at baseline, 1 and 2 weeks after dialysate is switched to glucose free dialysate. | — |
Countries
Sweden
Outcome results
None listed