Burn wound infection Skin and Connective Tissue Diseases Burn wound infection
Conditions
Interventions
The old dressing and exudate soaked gauze will be sent to the laboratory at University of Bath to assess the smart wound technology ‘switch-on’ i.e. colour change. A standard swab will be sent for rou
Sponsors
University Hospitals Bristol NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Control group 1. Patients with burns of all types and sizes 2. Any child from 4 weeks up to the age of 16 years/adults up to 100 years 3. >48 hrs after injury but before healing complete 4. Wound dressings intact 5. No signs of wound infection 6. Not currently using antibiotics 7. Consent gained for study Suspected infection group 1. Patients who present with a suspected burn wound infection as determined by the reference standard. 2. A child/adult with burns 3. Any child from 4 weeks up to the age of 16 years/adults up to 100 years 4. Wound dressings intact 5. Not on antibiotics for longer than 24 hours 6. Consent gained for study
Exclusion criteria
Exclusion criteria: All participants: 1. Child < four weeks of age/adults above 100 years 2. Consent not gained for study 3. Adult without mental capacity to consent 4. A child/adult who is on antibiotics for longer than 24 hours 5. No wound dressings
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Technology switched on or remained off is measured by observing colour change in the laboratory at baseline 2. Clinically relevant wound infection or no infection is assessed using clinical decisions, taking into account observation of wound, laboratory markers of inflammation and infection, wound and blood microscopy and culture and response to antibiotics at baseline. A follow-up review at 14-21 days will be carried out to confirm retrospectively the wound infection assessment at baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Levels of bacterial toxins to validate both clinical definition of wound infection and technology switch-on is measured using qPCR at baseline. | — |
Countries
United Kingdom
Contacts
Public ContactNatasha Iles
Outcome results
None listed