Cervical insufficiency Pregnancy and Childbirth
Conditions
Interventions
The modified transvaginal cervicoisthmic cerclage was performed by the same surgeon, assisted with one or two physicians. The preconceptional cerclage was performed with general anesthesia, and the ce
Sponsors
Health Bureau of Zhejiang Province
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 04/03/2019: 1. A history of at least 1 previous late inevitable abortion or spontaneous preterm delivery 2. Previous conization of the cervix or cervical laceration by assisted vaginal delivery, and the residual cervix is less than 25mm 3. All patients should be >=18 years and younger than 35 years old 4. All patients are able to conceive Previous inclusion criteria: 1. A history of at least 2 previous late inevitable abortion or spontaneous preterm delivery 2. Previous conization of the cervix or cervical laceration by assisted vaginal delivery, and the residual cervix is less than 25mm 3. All patients should be >=18 years and younger than 35 years old 4. All patients are able to conceive
Exclusion criteria
Exclusion criteria: 1. Older than 35 years old 2. Patients with a successful or failed cerclage applied in a previous pregnancy 3. Patients with congenital uterine dysplasia: Mediastinum uterus, bicornuate uterus, rudimentary horn of uterus, et al. 4. Patients with protein C, protein S, or antithrombin III de?ciency 5. Patients who are pregnant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The perinatal survival rate 2. The delivery gestational age | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Complications during pregnancy 2. The fetal weight | — |
Countries
China
Outcome results
None listed