Non-Suicidal Self-Injury (NSSI) comorbid with Major Depressive Disorder (MDD) or Persistent Depressive Disorder (PDD) in adolescents Mental and Behavioural Disorders
Conditions
Interventions
This study adopts a prospective, randomized controlled trial design in which eligible participants are allocated to either the intervention group or the control group at a 1:1 ratio. The randomization
chain analysis of non-suicidal self-injury (NSSI) behavior
mindfulness skills (wise mind
“what” and “how” skills)
emotion regulation (exploring emotions, building mastery and accumulating positive emotions, cope ahead and PLEASE skills, opposite action)
distress tolerance (distracting with ACCEPT
Sponsors
Wannan Medical College
Wuhu Fourth People Hospital
Eligibility
Sex/Gender
All
Age
14 Years to 19 Years
Inclusion criteria
Inclusion criteria: 1. Meeting DSM-5 diagnostic criteria for major depressive disorder or persistent depressive disorder, as confirmed by the MINI screening, and concurrently meeting DSM-5 diagnostic criteria for non-suicidal self-injury disorder (NSSI) 2. Aged between 14 and 19 years 3. Having at least a sixth-grade education level 4. If taking psychiatric medication, the type and dosage had been stable for at least one month 5. Providing written informed consent from both the participant and their legal guardian, as approved by the ethics committee
Exclusion criteria
Exclusion criteria: 1. Comorbid neurodevelopmental disorders, disruptive or conduct disorders 2. Comorbid schizophrenia or other psychotic disorders 3. Severe or acute physical or neurological disorders 4. Current suicide risk, defined as a score of =3 on the suicide item of the Hamilton Depression Rating Scale (HAMD-17) 5. Prior receipt of systematic DBT or receipt of modified electroconvulsive therapy within three months prior to enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Non-suicidal self-injury (NSSI), thoughts of NSSI, and suicide attempts measured using the Chinese version of the Ottawa Self-Injury Inventory (OSI), Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Rating Scale (HAMA), Cognitive Emotion Regulation Questionnaire (CERQ), Difficulties in Emotion Regulation Scale (DERS), Toronto Alexithymia Scale-20 (TAS-20), Mindful Attention Awareness Scale (MAAS), and the Barratt Impulsiveness Scale (Version 11, BIS-11), at baseline, mid-treatment, post-treatment, and at 3- and 6-month follow-ups | — |
Countries
China
Contacts
Public ContactBing-Qing Luo
Outcome results
None listed