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PiPS2: A study investigating predictions about how long patients with advanced cancer have left to live

The Prognosis in Palliative care Study II (PiPS2): A multicentre prospective, observational, validation cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN13688211
Enrollment
1390
Registered
2016-06-28
Start date
2016-07-01
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced incurable cancer Cancer Advanced incurable cancer

Interventions

This study will be investigating prognostic models in patients with advanced incurable cancer. These include the Prognosis in Palliative Care (PiPS) A and B predictor models, the Palliative Prognostic

Sponsors

University College London
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Participants with advanced incurable cancer 2. With or without capacity to consent to research 3. Aged 18 years or over 4. Have been recently referred to palliative care services

Exclusion criteria

Exclusion criteria: Currently receiving (or planned to receive) treatment with curative intent.

Design outcomes

Primary

MeasureTime frame
1. Survival of the participants are measured from date of study entry 2. Predictions of the PiPS-A and the PiPS-B prognostic models (whether a patient is likely to live for “days” (less than 14-days), “weeks” (2 to 7 weeks), or “months +” (2 months or more))

Secondary

MeasureTime frame
Predictions produced by the PPI (less than 3 week survival, 3 to 6 week survival, and greater than 6 week survival); PPS (probability of dying within 7, 14 or 28 days); FPN (risk of dying within 15, 30 or 60 days); PaP (risk of dying within 30 days).

Countries

England, United Kingdom, Wales

Contacts

Public ContactAnastasia Kalpakidou

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 5, 2026