Major depressive disorder Mental and Behavioural Disorders Major depressive disorder
Conditions
Interventions
Allocation to groups was done with a computer-generated random number table.
Arm 1 (Intervention) Cognitive Control Training:
18 sessions (twp per week) training execu
Sponsors
National Institute for Mental Health and Neuroscience (NIMHANS)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Major Depressive Disorder (as primary diagnosis) 2. Score of 17 or above on Beck’s Depression Inventory (BDI) 3. Age range of 18-50 years 4. Comprehension of written and spoken English/Hindi 5. Right handedness 6. Normal or corrected vision or hearing 7. Stable on medication dosage for one month
Exclusion criteria
Exclusion criteria: 1. History suggestive of neurological, neurosurgical conditions and /or history of head injury And/or mental retardation on clinical assessment 2. Diagnosis of schizophrenia, Bipolar Affective Disorder, Severe Depression with psychotic symptoms, Delusional disorder, current psychoactive substance abuse and/or dependence (except nicotine) 3. Any structured psychological intervention in the past 6 months 4. Any neurocognitive intervention and/or neuropsychological assessments 5. Have received ECT (in last 6 months)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression measured using Beck's Depression Inventory (BDI) at baseline and 9 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Illness severity measured using the Clinical Global Index (CGI) at baseline and 9 weeks 2. Neuro-cognitive measures at baseline and 9 weeks: 2.1. Spatial Span 2.2. Digit Span (WMS III) | — |
Countries
India
Contacts
Public ContactMeenakshi Banerjee
Outcome results
None listed