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Palliative care for multi-drug resistant tuberculosis (TB) in Uganda

Nurse-led integrated palliative care for multi drug resistant tuberculosis patients taking anti multi drug resistant TB therapy in Uganda: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN13664346
Enrollment
144
Registered
2020-08-14
Start date
2019-12-18
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multidrug-resistant tuberculosis Infections and Infestations Tuberculosis

Interventions

MDR TB patients who will have been randomly allocated to the intervention group will receive palliative care from palliative care specialist nurses who will receive a two days intensive integrated pal
follow up will be done once every week if a participant is still admitted on the ward and every two weeks if they are at home over the three months period of the study. However for every alternative w

Sponsors

King's College London
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 18 years and above 2. Diagnosis of MDR TB 3. Registered at the MDR TB clinic of the respective study sites 4. Willing to give informed consent

Exclusion criteria

Exclusion criteria: All MDR TB patients attending the respective study sites who are unable to memorize past events due to their impaired cognitive ability as judged by attending physicians and all those who cannot express themselves in English or local language will be excluded from this study.

Design outcomes

Primary

MeasureTime frame
Self-reported palliative care-related symptoms and concerns (measured using the Integrated APCA African POS) at baseline and then monthly for 4 months

Secondary

MeasureTime frame
At baseline and then monthly for 4 months: 1. Quality of life assessed using GHQ-12 and the World Health Organization quality of life (WHOQOL - BREF) assessment tool 2. Social support assessed using MOS Social Support Survey 3. Adherence to treatment which will be measured during clinical assessment using the Adherence and Alcohol tool 4. Service use measured with Client Services Receipt Inventory (CSRI)

Countries

Uganda

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 5, 2026