A randomised controlled trial comparing taurolidine-citrate with heparin for locking tunnelled haemodialysis catheters

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN13630682

Enrollment

164

Registered

2006-09-21

Start date

2006-10-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Renal Failure requiring treatment with regular haemodialysis Urological and Genital Diseases Chronic Renal Failure requiring treatment with regular haemodialysis

Interventions

One group will be randomised to receive taurolidine-citrate catheter lock solution and the other heparin 5000 iu/ml catheter lock solution. Added 18/02/2010: trial was stopped because objectives were

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Chronic renal failure requiring haemodialysis 2. Patients undergoing tunnelled haemodialysis catheter insertion

Exclusion criteria

Exclusion criteria: 1. Aged under 16 years 2. Known intolerance to heparin or taurolidine-citrate 3. Patients receiving antibiotic treatment

Design outcomes

Primary

Measure	Time frame
Rates of catheter-related bacteraemia	—

Secondary

Measure	Time frame
1. Rates of catheter occlusion 2. Mortality rate 3. Exit-site infection rates 4. Epoietin requirements 5. Hospitalisation 6. Haemodialysis adequacy	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026