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Does the sedative drug ketamine play a role in pain relief following wisdom teeth extractions?

The role of ketamine in post-operative analgesia following third molar surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN13624724
Enrollment
128
Registered
2017-04-24
Start date
2017-01-06
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wisdom teeth extractions Oral Health Wisdom teeth extractions

Interventions

Each patient would spend approximately 2 hours at the Oral and Maxillofacial surgery outpatient clinic at the Victoria General Hospital from pre-operative assessment, undergoing surgery, and to discha

Sponsors

Nova Scotia Health Authority Research Ethics Board
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Male and female 2. Aged 16 to 25 years old 3. Health status is ASA I or ASA II 4. Presence of at least 3 wisdom teeth 5. Wisdom teeth present are associated with disease such as cavities or periodontal condition or 6. Wisdom teeth are impacted and will not predictably erupt functionally into the dentition

Exclusion criteria

Exclusion criteria: 1. Patients younger than 16 and older than 25 years old 2. Patients with obvious pathology including cysts or tumors associated with wisdom tooth 3. Patients that are ASA class III or higher 4. Pregnant or lactating patients 5. Patients with fewer than 3 wisdom teeth for removal

Design outcomes

Primary

MeasureTime frame
Degree of post-operative pain experienced is assessed by use of a take-home questionnaire containing multiple scales to describe the intensity of post-operative pain experienced (from 0-10, with 0 being no pain and 10 being most intense pain) at 6 hour intervals for up to 48 hours following wisdom teeth surgery

Secondary

MeasureTime frame
Use of pain medication (including type and dosage) is assessed by use of a take-home questionnaire at 6 hour intervals for up to 48 hours following wisdom teeth surgery

Countries

Canada

Contacts

Public ContactJohnson Cheung

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026